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Osteoprotegerin ELISA Kit

In stock
Vendor code
K 1011

Osteoprotegerin (OPG) or osteoclast inhibitory factor (OCIF) is a glycoprotein of the TNF receptor superfamily 11b (gene name TNFRSF11B) http://www.uniprot.org/uniprot/O00300. OPG is synthesized as a monomer of 380 amino acids and is assembled as a homodimer within the cell, and then secreted mainly as a disulfide-linked homodimer into the extracellular compartment. OPG is produced by many different tissues and cell types including osteoblasts. OPG is a negative regulator of bone resorption by acting as decoy receptor for RANKL, thus neutralizing its function in osteoclastogenesis. This glycoprotein is also involved in the regulation of vascular calcification.

Indications

• Osteoporosis 1, 2

• Diseases with locally incr. resorption activity 3 - 6

• Arthritis 7, 8

• Therapy monitoring 9 - 11

• Cardiovascular Disease

  • Packing size
    24 х 17 х 12 cm
  • Manufacturer
    ImmunDiagnostic
  • Kit format
    96 × 1
  • Testing (Manual/Machine/Both)
    Manual and Machine
  • Use by a doctor
    No
  • Use by a patient
    No
  • POC
    No
  • Storage conditions
    +2 - +8 °C
  • Short Description

    This Immundiagnostik assay is a sandwich ELISA intended for the quantitative determination of osteoprotegerin in serum, EDTA plasma, heparin plasma or citrate plasma. It is for in vitro diagnostic use only.